It's derisively called "The Kennedy Touch" - the women who marry Kennedy men end up desperately unhappy. Used, absued, tossed aside like a piece of raw meat, the high profile philandering and substance abuse of Kennedy men makes life a living hell for many of their wives.

Yesterday, the wife of Robert Kennedy Jr. ended the pain by hanging herself on her estate in suburban New York.

New York Post:

Robert F. Kennedy Jr.'s estranged wife, Mary, who battled her husband's rumored philandering by turning to alcohol and prescription drugs, hanged herself in a barn on their Westchester estate yesterday, sources told The Post.

The 52-year-old mother of four -- the latest victim of a family dynasty cursed with tragedies -- may have taken her own life because she was haunted by her broken marriage, her friends lamented.

"She was deeply troubled, abusing alcohol and prescription meds," a close family friend said. "She had cause. She was used up and tossed away by Bobby. That was awful."

PHOTOS: OTHER KENNEDY FAMILY DEATHS

Officials refused to elaborate on her death and said it would be investigated with the Westchester Medical Examiner's Office.

Bedford police responded at 1:36 p.m. to a report of a "possible unattended death" -- meaning there were no witnesses -- at the estate.

After authorities arrived, they cut her down and tried to revive her. She was found by a housekeeper, ABC News reported.

Mary was found "inside an out-building on that property," police said in a statement.

She left behind a note, and none of her children were home at the time, sources said.

There are several sheds behind the home - some hold garden tools and another is a falcon house - on a slope leading to a lake.

The Kennedy family dealt stoically with the latest in the long line of shocking deaths.

"We deeply regret the death of our beloved sister Mary, whose radiant and creative spirit will be sorely missed by those who loved her," the family said in a statement.

"Our heart goes out to her children, who she loved without reservation. We have no further comment at this time."

A grim-faced RFK Jr. showed up at the house at around 8 p.m.

There is no "Kennedy curse" - a convenient cover up for the real reason Kennedys suffer tragedy. Outside of John and Robert who were assassinated, the deaths and heartache of other family members is largely a result of a clan that recognizes no boundaries - no appetites that can't be sated, no rules that apply to them, no behavior off limits. They feel themselves indestructible - and untouchable.

It is hubris and not bad luck that is the cause of unhappiness in that family. And Mary Kennedy got a lot more than she bargained for when she married into this arrogant, destructive, dysfunctional family.